Lichen Sclerosus Et Atrophicus

Lichen Sclerosus Et Atrophicus1

Lichen Sclerosus Et Atrophicus2

General Information

Lichen Sclerosus et Atrophicus is a chronic skin disease that causes pale to white plaques with epidermal atrophy. LSA may appear on areas such as the neck, under the breast, in folds of the body, and in the perianal and vulva. Itching may occur in some patients, but it is not common. If located in the genital areas thinning and shrinking may occur which may produce some pain. The cause is unknown but has been linked with an autoimmune process or an injury. Treatments consist of topical ointments, antipruritics, corticosteroids and testosterone to the affected area.

Women are more commonly affected, ages 40-60. Male to female ratio 1:6


Altered fibroblast function, microvascular changes, and hyaluronic acid accumulation in the upper dermis

Pale white elevations that may be flat and glistening

Lichenoid infiltrate in the dermal-epidermal junction, compact hyperkeratosis with stratum corneum

1. “Lichen Sclerosus et Atrophicus” (Online). December 2006. (visited: March 20, 2008) 2. “Lichen Sclerosus et Atrophicus” (Online). (visited: March 20, 2008)

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